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Clinical Consensus
Understanding U=U: The Science Behind Zero HIV Transmission Risk
By PozMeet Science Team
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Medically Reviewed by Dr. Marcus Thorne, MD
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Citations: CDC, Lancet PARTNER Trials
"Undetectable = Untransmittable" (U=U) is one of the most transformative public health breakthroughs in modern medicine.
What Does U=U Mean?
When a person living with HIV takes antiretroviral therapy (ART) as prescribed and maintains an undetectable viral load (<200 copies/mL) for at least 6 months, they have effectively zero risk of transmitting HIV to their sexual partners.
The Clinical Evidence
The landmark PARTNER 1 and PARTNER 2 studies published in The Lancet monitored over 100,000 condomless sex acts among serodifferent couples. The result: Zero linked transmissions occurred when the HIV-positive partner was undetectable.
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